List of publications - Prof. Dr. U. Hübscher

Crespan E, Czabany T, Maga G, Hübscher U
Microhomology-mediated DNA strand annealing and elongation by human DNA polymerases λ and β on normal and repetitive DNA sequences
Nucleic Acids Res. 2012 Feb 28

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Markkanen E, Hübscher U, van Loon B
Regulation of oxidative DNA damage repair: the adenine:8-oxo-guanine problem
Cell Cycle. 2012 Mar 15;11(6):1070-5

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Markkanen E, van Loon B, Ferrari E, Parsons JL, Dianov GL, Hübscher U
Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination
Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):437-42

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Crespan E, Maga G, Hübscher U
A new proofreading mechanism for lesion bypass by DNA polymerase-λ
EMBO Rep. 2011 Dec 23;13(1):68-74

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Eger S, Castrec B, Hübscher U, Scheffner M, Rubini M, Marx A
Generation of a Mono-ubiquitinated PCNA Mimic by Click Chemistry
Chembiochem. 2011 Dec 16;12(18):2807-12

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Meerang M, Ritz D, Paliwal S, Garajova Z, Bosshard M, Mailand N, Janscak P, Hübscher U, Meyer H, Ramadan K
The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks
Nat Cell Biol. 2011 Oct 23;13(11):1376-82

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Hübscher U, Maga G
DNA replication and repair bypass machines
Curr Opin Chem Biol. 2011 Oct;15(5):627-35

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Villani G, Hubscher U, Gironis N, Parkkinen S, Pospiech H, Shevelev I, di Cicco G, Markkanen E, Syväoja JE, Tanguy Le Gac N
In vitro gap-directed translesion DNA synthesis of an abasic site involving human DNA polymerases epsilon, lambda, and beta
J Biol Chem. 2011 Sep 16;286(37):32094-104

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Markkanen E, van Loon B, Ferrari E, Hübscher U.:
Ubiquitylation of DNA polymerase λ
FEBS Lett. 2011 Apr 8

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Locatelli, G.A., Pospiech, H., Tanguy Le Gac, N. , van Loon, B., Hübscher, U., Parkkinen, S., Syväoja, J. and Villani, G.
Effect of 8-oxo-guanine and abasic site DNA lesions on in vitro elongation by human DNA polymerase ε in presence of replication protein A and proliferating cell nuclear antigen
Biochem J., 429, 573-582, 2010

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van Loon, B., Markkanen, E. and Hübscher, U.
Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine
DNA repair, 9, 604-616, 2010

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van Loon, B and Hübscher, U
An 8-oxo-guanine reapir pathway coordinated by MUTYH glycosylase and DNA polymerase λ
Proc. Natl. Acad. Sci. USA , 106, 18201-18206, 2009

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van Loon, B., Ferrari, E. and Hübscher, U
Isolation of recombinant DNA elongation proteins
In: Methods in Molecular Biology, DNA replication, Eds.Vengrova, S. and Dalgaard, J. Humana Press Inc. 521, 345-359, 2009

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Hübscher, U
DNA replication fork proteins
In: Methods in Molecular Biology, DNA replication, Eds.Vengrova, S. and Dalgaard, J. Humana Press Inc. 521, 19-34, 2009

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Maga, G., van Loon, B., Crespan, E., Villani, G and Hübscher, U
The block of DNA polymerase δ strand displacement activity by an abasic site can be rescued by the concerted action of DNA polmyerase β and flap endonuclease 1
J. Biol. Chem., 284, 14267-14275, 2009

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