Publications - Dr. B. van Loon

Crespan E, Furrer A, Rösinger M, Bertolett F, Mentegari E, Chiapparini G, Imhof R, Ziegler N, Sturla SJ, Hübscher U, van Loon B, Maga G
Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair
Nat Commun. 2016 Feb 26;7:10805

PubMed Full Text Article

Nilforoushan A, Furrer A, Wyss LA, van Loon B, Sturla SJ
Nucleotides with Altered Hydrogen Bonding Capacities Impede Human DNA Polymerase η by Reducing Synthesis in the Presence of the Major Cisplatin DNA Adduct
J Am Chem Soc 2015 Apr 15;137(14):4728-34

PubMed Full Text Article

Furrer A, van Loon B
Handling the 3-methylcytosine lesion by six human DNA polymerases members of the B-, X- and Y-families
Nucleic Acids Res 2014;42(1):553-66

PubMed Full Text Article

Maga G, Crespan E, Markkanen E, Imhof R, Furrer A, Villani G, Hübscher U, van Loon B
DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass
Proc Natl Acad Sci U S A 2013;110(47):18850-5

PubMed Full Text Article

Pirinen E, Cantó C, Jo YS, Morato L, Zhang H, Menzies KJ, Williams EG, Mouchiroud L, Moullan N, Hagberg C, Li W, Timmers S, Imhof R, Verbeek J, Pujol A, van Loon B, Viscomi C, Zeviani M, Schrauwen P, Sauve AA, Schoonjans K, Auwerx J
Pharmacological Inhibition of Poly(ADP-Ribose) Polymerases Improves Fitness and Mitochondrial Function in Skeletal Muscle
Cell Metab 2014. pii: S1550-4131(14)00165-X

PubMed

van Loon B, Samson LD
Alkyladenine DNA glycosylase (AAG) localizes to mitochondria and interacts with mitochondrial single-stranded binding protein (mtSSB)
DNA Repair (Amst) 2013;12(3):177-87

PubMed Full Text Article

Bosshard M, Markkanen E, van Loon B
Base excision repair in physiology and pathology of the central nervous system
Int J Mol Sci 2012;13(12):16172-222

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Markkanen E, Hübscher U, van Loon B
Regulation of oxidative DNA damage repair: the adenine:8-oxo-guanine problem
Cell Cycle 2012;11(6):1070-5

PubMed Full Text Article

Markkanen E, van Loon B, Ferrari E, Parsons JL, Dianov GL, Hübscher U
Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination
Proc Natl Acad Sci U S A 2012;109(2):437-42

PubMed Full Text Article

van Loon B, Markkanen E, Hübscher U
Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine
DNA Repair (Amst) 2010 Jun 4;9(6):604-16

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van Loon B, Hübscher U
An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase lambda
Proc Natl Acad Sci U S A 2009;106(43):18201-6

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